antinociceptive activity of tribulus terrestris oral feeding in diabetic rats: involvement of lipid peroxidation

Antinociceptive activity of Tribulus terrestris oral feeding in diabetic rats: Involvement of lipid peroxidation

Background and Objective: Due to the presence of some evidence for anti-diabetic and antioxidant activity of Tribulus terrestris (TT), this study was designed to investigate the anti-nociceptive effect of TT in streptozotocin-diabetic rats using formalin test and hot tail immersion tests. Materials and Methods: Rats were divided into control, TT-treated control, diabetic, sodium salicylate (SS)...

Antinociceptive activity of Tribulus terrestris oral feeding in diabetic rats: Involvement of lipid peroxidation

Results: TT treatment of diabetic rats reduced pain score only in chronic phase of the formalin test (p<0.05). Meanwhile, SS administration significantly reduced pain score only at chronic phase of the test (p<0.05). Regarding hot tail immersion test, diabetic rats showed a significant reduction in tail flick latency as compared to control ones (p<0.05). Although TT treatment of diabetic rats i...

The Effect of Oral Feeding of Tribulus terrestris L. on Sex Hormone and Gonadotropin Levels in Addicted Male Rats

Antinociceptive effect of black seed feeding in streptozotocin-diabetic rats

  Abstract  Introduction: Diabetic rats display exaggerated hyperalgesic behavior in response to noxious stimuli that may resemble and model aspects of painful diabetic neuropathy in humans. This study was designed to investigate the effect of Nigella sativum (NS) on formalin-induced nociceptive responses (standard formalin test) in streptozotocin (STZ)-induced diabetic rats.  Methods: For this...

antinociceptive effect of curcumin, an effective constituent of turmeric, in diabetic rats and evaluation of the involvement of lipid peroxidation

objective: this study was designed to investigate the antinociceptive effect of curcumin in diabetic rats by using the formalin and hot tail immersion tests. methods: wistar rats were divided into the following six groups:  control; curcumin-treated control (50 mg/kg); diabetic; sodium salicylate (ss)-treated diabetic; and two curcumin-treated diabetic groups (10 and 50 mg/kg). curcumin was ad...

Nitric oxide and endothelium-dependent effect of Tribulus terrestris feeding on aortic reactivity of streptozotocin-diabetic rats

Background and Objective: Cardiovascular disorders continue to constitute major causes of morbidity and mortality in diabetic patients. In this study, the effect of chronic administration of Tribulus terrestris (TT) feeding was studied on aortic reactivity of streptozotocin (STZ)-diabetic rats and some underlying mechanisms were investigated.    Materials and Methods: Male diabetic rats receive...